Shingles
Shingles is a virus that causes a painful rash. It usually clears within four weeks, but can cause complications that may take a long time to resolve in some people.
In case anyone needed further encouragement to accept the shingles jab, a number of major research studies suggest that there has been a discernible decline in the number of dementia diagnoses. According to research published in journals like ‘Nature’ and ‘Nature Medicine’, older adults accepting the shingles vaccination have a markedly lower risk of developing dementia, compared to those who do not receive the vaccine.
Stanford Medicine published the results of research conducted with 280,000 older adults in Wales. It showed that in adults with early cognitive impairment the zoster vaccine cut the likelihood of dying from dementia in a nine-year period in half. A 2026 paper showed that two doses of the vaccine were linked to a 51% reduction in the risk of developing dementia. Though it has not been proven, it is seen as a potent contributory element.
Shingles is caused by the reactivation of the varicella herpes virus (chicken pox). The vaccine blocks the recurrence of the herpes-zoster virus which is dormant in the body after chickenpox. People who have not had chickenpox cannot develop shingles. However, it is not always easy to be sure that a person has not had chickenpox if it was a very mild case and not recognised as such. Additionally, chicken pox may be contracted from someone who has shingles through contact with fluid from the shingles blisters, for example.
Other vaccines, like those for the prevention of influenza, diptheria/ tetanus/pertussis, and RSV, may also play a role in reducing the risk of dementia. In short, anything that reduces the influence of systemic infections helps to protect the ageing brain.
Repurposing drugs approved for other conditions is a reliable and cost-effective way of providing treatments for many illnesses. New drugs can take 10 to 15 years to develop and test.
Two professors at the University of Exeter have found three drugs from a panel of 80 that could be the most helpful in treating and possibly preventing dementia. They are the shingles vaccine, (Zostavax), Viagra (Sildenafil), and one used for MND (Riluzole), with the shingles vaccine proving to be the most favourable, as it requires just two doses and has proved to be safe.


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